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Application of Random Mutagenesis and Synthetic FadR Promoter for de novo Production of ω-Hydroxy Fatty Acid in Yarrowia lipolytica

As a means to develop oleaginous biorefinery, Yarrowia lipolytica was utilized to produce ω-hydroxy palmitic acid from glucose using evolutionary metabolic engineering and synthetic FadR promoters for cytochrome P450 (CYP) expression. First, a base strain was constructed to produce free fatty acids...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Park, Beom Gi, Kim, Junyeob, Kim, Eun-Jung, Kim, Yechan, Kim, Joonwon, Kim, Jin Young, Kim, Byung-Gee
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937803/
https://ncbi.nlm.nih.gov/pubmed/33692989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.624838
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