Targeting a positive regulatory loop in the tumor-macrophage interaction impairs the progression of clear cell renal cell carcinoma

Although the interaction between tumors and tumor-associated macrophages (TAMs) has been reported to facilitate the targeted drug resistance and progression of clear cell renal cell carcinoma (ccRCC), the related mechanisms remain unknown. Here, we report that SOX17 serves as a novel tumor suppresso...

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Veröffentlicht in:Cell Death Differ
Hauptverfasser: Wang, Chao, Wang, Yuning, Hong, Tianyu, Ye, Jianqing, Chu, Chuanmin, Zuo, Li, Zhang, Jing, Cui, Xingang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937678/
https://ncbi.nlm.nih.gov/pubmed/33009518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00626-6
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