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CTCF Mediates Replicative Senescence Through POLD1
POLD1, the catalytic subunit of DNA polymerase δ, plays a critical role in DNA synthesis and DNA repair processes. Moreover, POLD1 is downregulated in replicative senescence to mediate aging. In any case, the components of age-related downregulation of POLD1 expression have not been fully explained....
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| Publicado en: | Front Cell Dev Biol |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7937641/ https://ncbi.nlm.nih.gov/pubmed/33692996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.618586 |
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