Small Bowel Resection Increases Paracellular Gut Barrier Permeability via Alterations of Tight Junction Complexes Mediated by Intestinal TLR4

BACKGROUND: Short bowel syndrome resulting from small bowel resection (SBR) is associated with significant morbidity and mortality. Many adverse sequelae including steatohepatitis and bacterial overgrowth are thought to be related to increased bacterial translocation, suggesting alterations in gut p...

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Udgivet i:J Surg Res
Main Authors: Courtney, Cathleen M., Onufer, Emily J., McDonald, Keely G., Steinberger, Allie E., Sescleifer, Anne M., Seiler, Kristen M., Tecos, Maria E., Newberry, Rodney D., Warner, Brad W.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937530/
https://ncbi.nlm.nih.gov/pubmed/33002664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2020.08.049
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