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High Expression of COX-2 Associated with the Depth of Invasion on Acral Melanoma by Increasing TGF-β1

INTRODUCTION: Acral melanoma (AM) has a poor prognosis since it is easily metastatic and resistant to chemo and immunotherapy. Cyclooxygenase-2 (COX-2) is an enzyme that plays a role in the carcinogenesis process. The increased expression of COX-2 has an impact on increasing levels of Myeloid-Derive...

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Detalhes bibliográficos
Publicado no:Clin Cosmet Investig Dermatol
Main Authors: Gipsyianti, Nastassa, Aziz, Afiati, Hernowo, Bethy S, Usman, Hermin A
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937396/
https://ncbi.nlm.nih.gov/pubmed/33688233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CCID.S285564
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