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Association of Pathogenic Missense and Nonsense Mutations in Mitochondrial COII Gene with Familial Adenomatous Polyposis (FAP)

Nuclear genetic mutations have been extensively investigated in solid tumors. However, the role of the mitochondrial genome remains uncertain. Since the metabolism of solid tumors is associated with aerobic glycolysis and high lactate production, tumors may have mitochondrial dysfunctions. Familial...

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Bibliografiske detaljer
Udgivet i:Int J Mol Cell Med
Main Authors: Shaker Ardakani, Zahra, Heidari, Mohammad Mehdi, Khatami, Mehri, Bitaraf Sani, Morteza
Format: Artigo
Sprog:Inglês
Udgivet: Babol University of Medical Sciences 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7936074/
https://ncbi.nlm.nih.gov/pubmed/33688483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22088/IJMCM.BUMS.9.4.255
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