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Expanding the drug discovery space with predicted metabolite–target interactions

Metabolites produced in the human gut are known modulators of host immunity. However, large-scale identification of metabolite–host receptor interactions remains a daunting challenge. Here, we employed computational approaches to identify 983 potential metabolite–target interactions using the Inflam...

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Bibliographic Details
Published in:Commun Biol
Main Authors: Nuzzo, Andrea, Saha, Somdutta, Berg, Ellen, Jayawickreme, Channa, Tocker, Joel, Brown, James R.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935942/
https://ncbi.nlm.nih.gov/pubmed/33674782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01822-x
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