Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE

Transposable elements (TEs) make up a majority of a typical eukaryote’s genome, and contribute to cell heterogeneity in unclear ways. Single-cell sequencing technologies are powerful tools to explore cells, however analysis is typically gene-centric and TE expression has not been addressed. Here, we...

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Udgivet i:Nat Commun
Main Authors: He, Jiangping, Babarinde, Isaac A., Sun, Li, Xu, Shuyang, Chen, Ruhai, Shi, Junjie, Wei, Yuanjie, Li, Yuhao, Ma, Gang, Zhuang, Qiang, Hutchins, Andrew P., Chen, Jiekai
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935913/
https://ncbi.nlm.nih.gov/pubmed/33674594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21808-x
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