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Expression of asporin reprograms cancer cells to acquire resistance to oxidative stress

Asporin (ASPN), a small leucine‐rich proteoglycan expressed predominantly by cancer associated fibroblasts (CAFs), plays a pivotal role in tumor progression. ASPN is also expressed by some cancer cells, but its biological significance is unclear. Here, we investigated the effects of ASPN expression...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Sasaki, Yuto, Takagane, Kurara, Konno, Takumi, Itoh, Go, Kuriyama, Sei, Yanagihara, Kazuyoshi, Yashiro, Masakazu, Yamada, Satoru, Murakami, Shinya, Tanaka, Masamitsu
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935789/
https://ncbi.nlm.nih.gov/pubmed/33393151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14794
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