Genetic ablation of fibroblast activation protein alpha attenuates left ventricular dilation after myocardial infarction

INTRODUCTION: Regulating excessive activation of fibroblasts may be a promising target to optimize extracellular matrix deposition and myocardial stiffness. Fibroblast activation protein alpha (FAP) is upregulated in activated fibroblasts after myocardial infarction (MI), and alters fibroblast migra...

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Udgivet i:PLoS One
Main Authors: Hoffmann, Daniel B., Fraccarollo, Daniela, Galuppo, Paolo, Frantz, Stefan, Bauersachs, Johann, Tillmanns, Jochen
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935287/
https://ncbi.nlm.nih.gov/pubmed/33667270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0248196
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