YAP Circular RNA, circYap, Attenuates Cardiac Fibrosis via Binding with Tropomyosin-4 and Gamma-Actin Decreasing Actin Polymerization

Cardiac fibrosis is a common pathological feature of cardiac hypertrophy. This study was designed to investigate a novel function of Yes-associated protein (YAP) circular RNA, circYap, in modulating cardiac fibrosis and the underlying mechanisms. By circular RNA sequencing, we found that three out o...

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Veröffentlicht in:Mol Ther
Hauptverfasser: Wu, Nan, Xu, Jindong, Du, William W., Li, Xiangmin, Awan, Faryal Mehwish, Li, Feiya, Misir, Sema, Eshaghi, Esra, Lyu, Juanjuan, Zhou, Le, Zeng, Kaixuan, Adil, Aisha, Wang, Sheng, Yang, Burton B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2021
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934790/
https://ncbi.nlm.nih.gov/pubmed/33279723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.12.004
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