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Synthesis of (Z)-3-[amino(phenyl)methylidene]-1,3-dihydro-2H-indol-2-ones using an Eschenmoser coupling reaction

A highly modular method for the synthesis of (Z)-3-[amino(phenyl/methyl)methylidene]-1,3-dihydro-2H-indol-2-ones starting from easily available 3-bromooxindoles or (2-oxoindolin-3-yl)triflate and thioacetamides or thiobenzamides is described. A series of 49 compounds, several of which have previousl...

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Dettagli Bibliografici
Pubblicato in:Beilstein J Org Chem
Autori principali: Marek, Lukáš, Kolman, Lukáš, Váňa, Jiří, Svoboda, Jan, Hanusek, Jiří
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934781/
https://ncbi.nlm.nih.gov/pubmed/33727976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.17.47
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