DNA Damage Repair Gene Mutations Are Indicative of a Favorable Prognosis in Colorectal Cancer Treated With Immune Checkpoint Inhibitors

BACKGROUND: DNA damage repair (DDR) genes were recently implicated in the anti-tumor immune response. Therefore, it is worthwhile to unravel the implications of DDR pathways in the shaping of immune responsiveness in colorectal cancer (CRC) patients receiving immune checkpoint inhibitors (ICI). METH...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Oncol
Auteurs principaux: Song, Yipeng, Huang, Jian, Liang, Dandan, Hu, Ying, Mao, Beibei, Li, Qiujing, Sun, Huaibo, Yang, Ying, Zhang, Jiao, Zhang, Henghui, Chen, Huan, Liu, Hao, Zhang, Shukun
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Oncology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934780/
https://ncbi.nlm.nih.gov/pubmed/33680909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.549777
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