Inhibition of lncRNA MAAT Controls Multiple Types of Muscle Atrophy by cis- and trans-Regulatory Actions

Muscle atrophy is associated with negative outcomes in a variety of diseases. Identification of a common therapeutic target would address a significant unmet clinical need. Here, we identify a long non-coding RNA (lncRNA) (muscle-atrophy-associated transcript, lncMAAT) as a common regulator of skele...

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Publicat a:Mol Ther
Autors principals: Li, Jin, Yang, Tingting, Tang, Haifei, Sha, Zhao, Chen, Rui, Chen, Lei, Yu, Yan, Rowe, Glenn C., Das, Saumya, Xiao, Junjie
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2021
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934634/
https://ncbi.nlm.nih.gov/pubmed/33279721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.12.002
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