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ADAR1 Stimulation by IFN-α Downregulates the Expression of MAVS via RNA Editing to Regulate the Anti-HBV Response

The partial response of chronic hepatitis B virus (CHB) patients to interferon-α (IFN-α) therapy remains elusive, which requires a better understanding of the involved molecular mechanism. In our study, bioinformatics analysis was applied to relate IFN-α regulated candidate genes and RNA editing sit...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Ther
Auteurs principaux: Li, Tao, Yang, Xiaoshuang, Li, Wei, Song, Jiaru, Li, Zhuo, Zhu, Xilin, Wu, Xiaopan, Liu, Ying
Format: Artigo
Langue:Inglês
Publié: American Society of Gene & Cell Therapy 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934633/
https://ncbi.nlm.nih.gov/pubmed/33279720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.11.031
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