The Halastavi árva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism

Dicistrovirus intergenic region internal ribosomal entry sites (IGR IRESs) do not require initiator tRNA, an AUG codon, or initiation factors and jump-start translation from the middle of the elongation cycle via formation of IRES/80S complexes resembling the pre-translocation state. eEF2 then trans...

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Udgivet i:Cell Rep
Main Authors: Abaeva, Irina S., Vicens, Quentin, Bochler, Anthony, Soufari, Heddy, Simonetti, Angelita, Pestova, Tatyana V., Hashem, Yaser, Hellen, Christopher U.T.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934607/
https://ncbi.nlm.nih.gov/pubmed/33296660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108476
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