lnc-MAP3K13-7:1 Inhibits Ovarian GC Proliferation in PCOS via DNMT1 Downregulation-Mediated CDKN1A Promoter Hypomethylation

Polycystic ovary syndrome (PCOS) is an endocrine-related disease and global cause of infertility that is associated with abnormal folliculogenesis. Inhibited granulosa cell (GC) proliferation is recognized as a key factor that underlies aberrant follicle maturation. Many epigenetic landscape modific...

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Publicat a:Mol Ther
Autors principals: Geng, Xueying, Zhao, Jun, Huang, Jiayu, Li, Shang, Chu, Weiwei, Wang, Wang-sheng, Chen, Zi-Jiang, Du, Yanzhi
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2021
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934583/
https://ncbi.nlm.nih.gov/pubmed/33212300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.11.018
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