Genome-wide epistasis analysis for Alzheimer’s disease and implications for genetic risk prediction

BACKGROUND: Single-nucleotide polymorphisms (SNPs) identified by genome-wide association studies only explain part of the heritability of Alzheimer’s disease (AD). Epistasis has been considered as one of the main causes of “missing heritability” in AD. METHODS: We performed genome-wide epistasis scr...

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Detaylı Bibliyografya
Yayımlandı:Alzheimers Res Ther
Asıl Yazarlar: Wang, Hui, Bennett, David A., De Jager, Philip L., Zhang, Qing-Ye, Zhang, Hong-Yu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2021
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934265/
https://ncbi.nlm.nih.gov/pubmed/33663605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-021-00794-8
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