HDAC inhibitors suppress the proliferation, migration and invasiveness of human head and neck squamous cell carcinoma cells via p63-mediated tight junction molecules and p21-mediated growth arrest

In human head and neck squamous cell carcinoma (HNSCC), the invasion and metastatic properties of cancer cells are promoted by junctional adhesion molecule-A (JAM-A) and claudin-1; these are epithelial tight junction molecules regulated by histone deacetylases (HDACs) and transcription factor p63. H...

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Publicado no:Oncol Rep
Main Authors: Kakiuchi, Akito, Kakuki, Takuya, Ohwada, Kizuku, Kurose, Makoto, Kondoh, Atsushi, Obata, Kazufumi, Nomura, Kazuaki, Miyata, Ryo, Kaneko, Yakuto, Konno, Takumi, Kohno, Takayuki, Himi, Tetsuo, Takano, Ken-Ichi, Kojima, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934225/
https://ncbi.nlm.nih.gov/pubmed/33649777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2021.7997
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