STAT3 Silencing and TLR7/8 Pathway Activation Repolarize and Suppress Myeloid-Derived Suppressor Cells From Breast Cancer Patients

Cancer cells escape immune destruction. From this perspective, myeloid-derived suppressor cells (MDSCs), which are immunosuppressive in various cancers including breast cancer (BC), are significant. However, the precise mechanisms are unknown. We isolated HLA-DR(-)CD33(+) MDSCs and CD3(+) T cells fr...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Safarzadeh, Elham, Mohammadi, Ali, Mansoori, Behzad, Duijf, Pascal H. G., Hashemzadeh, Shahryar, Khaze, Vahid, Kazemi, Tohid, Derakhshani, Afshin, Silvestris, Nicola, Baradaran, Behzad
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933669/
https://ncbi.nlm.nih.gov/pubmed/33679700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.613215
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