Phenotypic Characterization and Brain Structure Analysis of Calcium Channel Subunit α(2)δ-2 Mutant (Ducky) and α(2)δ Double Knockout Mice

Auxiliary α(2)δ subunits of voltage-gated calcium channels modulate channel trafficking, current properties, and synapse formation. Three of the four isoforms (α(2)δ-1, α(2)δ-2, and α(2)δ-3) are abundantly expressed in the brain; however, of the available knockout models, only α(2)δ-2 knockout or mu...

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Detalhes bibliográficos
Publicado no:Front Synaptic Neurosci
Main Authors: Geisler, Stefanie M., Benedetti, Ariane, Schöpf, Clemens L., Schwarzer, Christoph, Stefanova, Nadia, Schwartz, Arnold, Obermair, Gerald J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933509/
https://ncbi.nlm.nih.gov/pubmed/33679366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2021.634412
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