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Structure and inhibition mechanism of the human citrate transporter NaCT
Citrate is most well-known as an intermediate in the TCA cycle of the cell. In addition to this essential role in energy metabolism, the tricarboxylate anion also acts as both a precursor and a regulator of fatty acid synthesis (1–3). Thus, the rate of fatty acid synthesis correlates directly with t...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7933130/ https://ncbi.nlm.nih.gov/pubmed/33597751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-021-03230-x |
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