Disruption of Dense Granular Protein 2 (GRA2) Decreases the Virulence of Neospora caninum

Neospora caninum causes abortions in cattle and nervous system dysfunction in dogs. Dense granular proteins (GRAs) play important roles in virulence; however, studies on NcGRA functions are limited. In the present study, multiple methods, including site-directed mutagenesis; CRISPR/Cas9 gene editing...

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Vydáno v:Front Vet Sci
Hlavní autoři: Dong, Jingquan, Zhang, Nan, Zhao, Panpan, Li, Jianhua, Cao, Lili, Wang, Xiaocen, Li, Xin, Yang, Ju, Zhang, Xichen, Gong, Pengtao
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Veterinary Science
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933011/
https://ncbi.nlm.nih.gov/pubmed/33681332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fvets.2021.634612
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