Identification of the SRC-family tyrosine kinase HCK as a therapeutic target in mantle cell lymphoma

Mantle cell lymphoma (MCL) is an aggressive non-Hodgkin lymphoma subtype arising from naïve B cells. Although novel therapeutics have improved patient prognosis, drug resistance remains a key problem. Here, we show that the SRC-family tyrosine kinase hematopoietic cell kinase (HCK), which is primari...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Lantermans, Hildo C., Minderman, Marthe, Kuil, Annemieke, Kersten, Marie-José, Pals, Steven T., Spaargaren, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932922/
https://ncbi.nlm.nih.gov/pubmed/32591642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-020-0934-6
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