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Evaluating Combined Precursor Isotopic Labeling and Isobaric Tagging Performance on Orbitraps To Study the Peripheral Proteome of Alzheimer’s Disease

Combined precursor isotopic labeling and isobaric tagging (cPILOT) is an enhanced multiplexing strategy currently capable of analyzing up to 24 samples simultaneously. This capability is especially helpful when studying multiple tissues and biological replicates in models of disease, such as Alzheim...

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Udgivet i:Anal Chem
Main Authors: King, Christina D., Robinson, Renã A. S.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932850/
https://ncbi.nlm.nih.gov/pubmed/31940168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b01974
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