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A convenient approach to synthesize substituted 5-Arylidene-3-m-tolyl thiazolidine-2, 4-diones by using morpholine as a catalyst and its theoretical study

Thiazolidinediones are very important and used as a drug for the treatment of type 2 diabetes. Here, we report a convenient approach to synthesis 3-m-tolyl-5-arylidene-2,4-thiazolidinediones (TZDs) derivatives 7a-e in two steps with moderate to good yield using morpholine as a catalyst. All the stru...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jahan, Khorshada, Khan, Kaif Rashid, Akhter, Kawsari, Romman, Umme Kulsum Rowzatur, Halim, Ershad
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932548/
https://ncbi.nlm.nih.gov/pubmed/33661961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247619
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