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DeepSRE: Identification of sterol responsive elements and nuclear transcription factors Y proximity in human DNA by Convolutional Neural Network analysis

SREBP1 and 2, are cholesterol sensors able to modulate cholesterol-related gene expression responses. SREBPs binding sites are characterized by the presence of multiple target sequences as SRE, NFY and SP1, that can be arranged differently in different genes, so that it is not easy to identify the b...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Noto, Davide, Giammanco, Antonina, Spina, Rossella, Fayer, Francesca, Cefalù, Angelo B., Averna, Maurizio R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932541/
https://ncbi.nlm.nih.gov/pubmed/33661949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247402
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