The pronounced lung lesions developing in LAT(Y136F) knock-in mice mimic human IgG4-related lung disease

RATIONALE: Immunoglobulin (Ig) G4-related disease (IgG4-RD) is a novel clinical disease entity characterized by an elevated serum IgG4 concentration and tumefaction or tissue infiltration by IgG4-positive plasma cells. Pathological changes are most frequently seen in the pancreas, lacrimal glands, a...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Waseda, Yuko, Yamada, Kazunori, Mizuguchi, Keishi, Ito, Kiyoaki, Watanabe, Satoshi, Zuka, Masahiko, Ishizuka, Tamotsu, Malissen, Marie, Malissen, Bernard, Kawano, Mitsuhiro, Matsui, Shoko
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932159/
https://ncbi.nlm.nih.gov/pubmed/33661938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247173
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