No Clinically Relevant Effect of Heart Rate Increase and Heart Rate Recovery During Exercise on Cardiovascular Disease: A Mendelian Randomization Analysis

BACKGROUND: Reduced heart rate (HR) increase (HRI), recovery (HRR), and higher resting HR are associated with cardiovascular (CV) disease, but causal inferences have not been deduced. We investigated causal effects of HRI, HRR, and resting HR on CV risk, all-cause mortality (ACM), atrial fibrillatio...

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Bibliografske podrobnosti
izdano v:Front Genet
Main Authors: Mensah-Kane, Josephine, Schmidt, Amand F., Hingorani, Aroon D., Finan, Chris, Chen, Yutang, van Duijvenboden, Stefan, Orini, Michele, Lambiase, Pier D., Tinker, Andrew, Marouli, Eirini, Munroe, Patricia B., Ramírez, Julia
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Genetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931909/
https://ncbi.nlm.nih.gov/pubmed/33679875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.569323
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