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Miniaturized filter-aided sample preparation (MICRO-FASP) method for high throughput, ultrasensitive proteomics sample preparation reveals proteome asymmetry in Xenopus laevis embryos

We report a miniaturized Filter Aided Sample Preparation method (micro-FASP) for low-loss preparation of submicrogram proteomic samples. The method employs a filter with ~0.1 mm(2) surface area, reduces the total volume of reagents to < 10 μL, and requires only two sample transfer steps. The meth...

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Vydáno v:Anal Chem
Hlavní autoři: Zhang, Zhenbin, Dubiak, Kyle M., Huber, Paul W., Dovichi, Norman J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931810/
https://ncbi.nlm.nih.gov/pubmed/32125139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c00470
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