T-cell CX3CR1 expression as a dynamic blood-based biomarker of response to immune checkpoint inhibitors

Immune checkpoint inhibitors (ICI) have revolutionized treatment for various cancers; however, durable response is limited to only a subset of patients. Discovery of blood-based biomarkers that reflect dynamic change of the tumor microenvironment, and predict response to ICI, will markedly improve c...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yamauchi, Takayoshi, Hoki, Toshifumi, Oba, Takaaki, Jain, Vaibhav, Chen, Hongbin, Attwood, Kristopher, Battaglia, Sebastiano, George, Saby, Chatta, Gurkamal, Puzanov, Igor, Morrison, Carl, Odunsi, Kunle, Segal, Brahm H., Dy, Grace K., Ernstoff, Marc S., Ito, Fumito
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930182/
https://ncbi.nlm.nih.gov/pubmed/33658501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21619-0
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