Genotype-phenotype correlation of tracheal cartilaginous sleeves and Fgfr2 mutations in mice

OBJECTIVES: To characterize tracheal cartilage morphology in mouse models of Fgfr2-related craniosynostosis syndromes. To establish relationships between specific Fgfr2 mutations and tracheal cartilaginous sleeve (TCS) phenotypes in these mouse models. METHODS: Postnatal day-0 knock-in mouse lines w...

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Detalhes bibliográficos
Publicado no:Laryngoscope
Main Authors: Lam, Austin S, Liu, C Carrie, Deutsch, Gail H, Rivera, Joshua, Perkins, Jonathan A, Holmes, Greg, Jabs, Ethylin Wang, Cunningham, Michael L, Dahl, John P
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930142/
https://ncbi.nlm.nih.gov/pubmed/32886384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.29060
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