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Comprehensive metabolomic study of the response of HK-2 cells to hyperglycemic hypoxic diabetic-like milieu

Diabetic nephropathy (DN) is the leading cause of chronic kidney disease. Although hyperglycaemia has been determined as the most important risk factor, hypoxia also plays a relevant role in the development of this disease. In this work, a comprehensive metabolomic study of the response of HK-2 cell...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Valdés, Alberto, Lucio-Cazaña, Francisco J., Castro-Puyana, María, García-Pastor, Coral, Fiehn, Oliver, Marina, María Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930035/
https://ncbi.nlm.nih.gov/pubmed/33658594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84590-2
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