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The role of wild-type tau in Alzheimer’s disease and related tauopathies

Tau oligomers have recently emerged as the principal toxic species in Alzheimer’s disease (AD) and tauopathies. Tau oligomers are spontaneously self-assembled soluble tau proteins that are formed prior to fibrils, and they have been shown to play a central role in neuronal cell death and in the indu...

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Pubblicato in:J Life Sci (Westlake Village)
Autori principali: Lo, Chih Hung, Sachs, Jonathan N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7929479/
https://ncbi.nlm.nih.gov/pubmed/33665646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.36069/jols/20201201
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