Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process

Polycystic ovary syndrome (PCOS) is the most common reproductive and metabolic disorder affecting women of reproductive age. PCOS has a strong heritable component, but its pathogenesis has been unclear. Here, we performed RNA sequencing and genome-wide DNA methylation profiling of ovarian tissue fro...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Mimouni, Nour El Houda, Paiva, Isabel, Barbotin, Anne-Laure, Timzoura, Fatima Ezzahra, Plassard, Damien, Le Gras, Stephanie, Ternier, Gaetan, Pigny, Pascal, Catteau-Jonard, Sophie, Simon, Virginie, Prevot, Vincent, Boutillier, Anne-Laurence, Giacobini, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7928942/
https://ncbi.nlm.nih.gov/pubmed/33539777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2021.01.004
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