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Integration of genetically regulated gene expression and pharmacological library provides therapeutic drug candidates

Approaches toward new therapeutics using disease genomics, such as genome-wide association study (GWAS), are anticipated. Here, we developed Trans-Phar [integration of transcriptome-wide association study (TWAS) and pharmacological database], achieving in silico screening of compounds from a large-s...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Konuma, Takahiro, Ogawa, Kotaro, Okada, Yukinori
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7928862/
https://ncbi.nlm.nih.gov/pubmed/33577681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddab049
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