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TOR functions as a molecular switch connecting an iron cue with host innate defense against bacterial infection

As both host and pathogen require iron for survival, iron is an important regulator of host-pathogen interactions. However, the molecular mechanism by which how the availability of iron modulates host innate immunity against bacterial infections remains largely unknown. Using the metazoan Caenorhabd...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Ma, Yi-Cheng, Dai, Li-Li, Qiu, Bei-Bei, Zhou, Ying, Zhao, Yu-Qiang, Ran, Yu, Zhang, Ke-Qin, Zou, Cheng-Gang
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7928448/
https://ncbi.nlm.nih.gov/pubmed/33657091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009383
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