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Ginkgolide B Maintains Calcium Homeostasis in Hypoxic Hippocampal Neurons by Inhibiting Calcium Influx and Intracellular Calcium Release

Ginkgolide B (GB), a terpene lactone and active ingredient of Ginkgo biloba, shows protective effects in neuronal cells subjected to hypoxia. We investigated whether GB might protect neurons from hypoxic injury through regulation of neuronal Ca(2+) homeostasis. Primary hippocampal neurons subjected...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Cell Neurosci
Prif Awduron: Wang, Li, Lei, Quan, Zhao, Shuai, Xu, WenJuan, Dong, Wei, Ran, JiHua, Shi, QingHai, Fu, JianFeng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7928385/
https://ncbi.nlm.nih.gov/pubmed/33679323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.627846
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