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Three-dimensional model of glioblastoma by co-culturing tumor stem cells with human brain organoids

Emerging three-dimensional (3D) cultures of glioblastoma are becoming powerful models to study glioblastoma stem cell behavior and the impact of cell–cell and cell–microenvironment interactions on tumor growth and invasion. Here we describe a method for culturing human glioblastoma stem cells (GSCs)...

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Dettagli Bibliografici
Pubblicato in:Biol Open
Autori principali: Azzarelli, Roberta, Ori, Michela, Philpott, Anna, Simons, Benjamin D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7928227/
https://ncbi.nlm.nih.gov/pubmed/33619017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.056416
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