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Failure of CD4 T Cell-Deficient Hosts To Control Chronic Nontyphoidal Salmonella Infection Leads to Exacerbated Inflammation, Chronic Anemia, and Altered Myelopoiesis

Immunocompromised patients are more susceptible to recurrent nontyphoidal Salmonella (NTS) bacteremia. A key manifestation of HIV infection is the loss of CD4 T cells, which are crucial for immunity to Salmonella infection. We characterized the consequences of CD4 T cell depletion in mice where viru...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Loomis, Wendy P., Delaney, Martha A., Johnson, Matthew L., Cookson, Brad T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927941/
https://ncbi.nlm.nih.gov/pubmed/33046510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00417-20
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