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Enhanced proliferation of Ly6C+ monocytes/macrophages contributes to chronic inflammation in skin wounds of diabetic mice

Diabetic wounds are characterized by persistent accumulation of pro-inflammatory monocytes/macrophages (Mo/MΦ) and impaired healing. However, the mechanisms underlying the persistent accumulation of Mo/MΦ remain poorly understood. Here, we report that Ly6C+F4/80lo/- Mo/MΦ proliferate at higher rates...

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Publicat a:J Immunol
Autors principals: Pang, Jingbo, Maienschein-Cline, Mark, Koh, Timothy J.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927918/
https://ncbi.nlm.nih.gov/pubmed/33443065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000935
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