Pharmacokinetics and Time-Kill Study of Inhaled Antipseudomonal Bacteriophage Therapy in Mice

Inhaled bacteriophage (phage) therapy is a potential alternative to conventional antibiotic therapy to combat multidrug-resistant (MDR) Pseudomonas aeruginosa infections. However, pharmacokinetics (PK) and pharmacodynamics (PD) of phages are fundamentally different from antibiotics and the lack of u...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Chow, Michael Y. T., Chang, Rachel Yoon Kyung, Li, Mengyu, Wang, Yuncheng, Lin, Yu, Morales, Sandra, McLachlan, Andrew J., Kutter, Elizabeth, Li, Jian, Chan, Hak-Kim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927809/
https://ncbi.nlm.nih.gov/pubmed/33077657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01470-20
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