Bacteriophage AB-SA01 Cocktail in Combination with Antibiotics against MRSA-VISA Strain in an In Vitro Pharmacokinetic/Pharmacodynamic Model

This study aimed to test the efficacy of bacteriophage-antibiotic combinations (BACs) in vitro in 24-h time-kill settings and in ex vivo simulated endocardial vegetation (SEV) pharmacokinetic/pharmacodynamic models for 96 h. BACs prevented the development of bacteriophage resistance, while some bact...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Kebriaei, Razieh, Lev, Katherine L., Stamper, Kyle C., Lehman, Susan M., Morales, Sandra, Rybak, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927802/
https://ncbi.nlm.nih.gov/pubmed/33077648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01863-20
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