A Micropatterned Human‐Specific Neuroepithelial Tissue for Modeling Gene and Drug‐Induced Neurodevelopmental Defects

The generation of structurally standardized human pluripotent stem cell (hPSC)‐derived neural embryonic tissues has the potential to model genetic and environmental mediators of early neurodevelopmental defects. Current neural patterning systems have so far focused on directing cell fate specificati...

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Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Sahni, Geetika, Chang, Shu‐Yung, Meng, Jeremy Teo Choon, Tan, Jerome Zu Yao, Fatien, Jean Jacques Clement, Bonnard, Carine, Utami, Kagistia Hana, Chan, Puck Wee, Tan, Thong Teck, Altunoglu, Umut, Kayserili, Hülya, Pouladi, Mahmoud, Reversade, Bruno, Toh, Yi‐Chin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927627/
https://ncbi.nlm.nih.gov/pubmed/33717833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202001100
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