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An RGDKGE-Containing Cryptic Collagen Fragment Regulates Phosphorylation of Large Tumor Suppressor Kinase-1 and Controls Ovarian Tumor Growth by a Yes-Associated Protein–Dependent Mechanism

The growth and spread of malignant tumors, such as ovarian carcinomas, are governed in part by complex interconnected signaling cascades occurring between stromal and tumor cells. These reciprocal cross-talk signaling networks operating within the local tissue microenvironment may enhance malignant...

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Publicat a:Am J Pathol
Autors principals: Han, XiangHua, Caron, Jennifer M., Lary, Christine W., Sathyanarayana, Pradeep, Vary, Calvin, Brooks, Peter C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927278/
https://ncbi.nlm.nih.gov/pubmed/33307038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.11.009
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