KRAS(G12C) Can Either Promote or Impair Cap-Dependent Translation in Two Different Lung Adenocarcinoma Cell Lines

KRAS(G12C) is among the most common oncogenic mutations in lung adenocarcinoma and a promising target for treatment by small-molecule inhibitors. KRAS oncogenic signaling is responsible for modulation of tumor microenvironment, with translation factors being among the most prominent deregulated targ...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Kyriakopoulos, George, Katopodi, Vicky, Skeparnias, Ilias, Kaliatsi, Eleni G., Grafanaki, Katerina, Stathopoulos, Constantinos
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7926983/
https://ncbi.nlm.nih.gov/pubmed/33672357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22042222
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