Aerosolized Exposure to H5N1 Influenza Virus Causes Less Severe Disease Than Infection via Combined Intrabronchial, Oral, and Nasal Inoculation in Cynomolgus Macaques

Infection with highly pathogenic avian H5N1 influenza virus in humans often leads to severe respiratory disease with high mortality. Experimental infection in non-human primates can provide additional insight into disease pathogenesis. However, such a model should recapitulate the disease symptoms o...

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Bibliografiske detaljer
Udgivet i:	Viruses
Main Authors:	Mooij, Petra, Stammes, Marieke A., Mortier, Daniella, Fagrouch, Zahra, van Driel, Nikki, Verschoor, Ernst J., Kondova, Ivanela, Bogers, Willy M. J. M., Koopman, Gerrit
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI 2021
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7926951/ https://ncbi.nlm.nih.gov/pubmed/33671829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13020345
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Aerosolized Exposure to H5N1 Influenza Virus Causes Less Severe Disease Than Infection via Combined Intrabronchial, Oral, and Nasal Inoculation in Cynomolgus Macaques

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