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Wnt/β-Catenin Signaling Regulates CXCR4 Expression and [(68)Ga] Pentixafor Internalization in Neuroendocrine Tumor Cells

Loss of Somatostatin Receptor 2 (SSTR2) expression and rising CXC Chemokine Receptor Type 4 (CXCR4) expression are associated with dedifferentiation in neuroendocrine tumors (NET). In NET, CXCR4 expression is associated with enhanced metastatic and invasive potential and worse prognosis but might be...

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Detalhes bibliográficos
Publicado no:Diagnostics (Basel)
Main Authors: Weich, Alexander, Rogoll, Dorothee, Gawlas, Sophia, Mayer, Lars, Weich, Wolfgang, Pongracz, Judit, Kudlich, Theodor, Meining, Alexander, Scheurlen, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7926465/
https://ncbi.nlm.nih.gov/pubmed/33671498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diagnostics11020367
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