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Biochemical Regulation of the Glyoxalase System in Response to Insulin Signaling

Methylglyoxal (MG) is a reactive glycation metabolite and potentially induces dicarbonyl stress. The production of MG in cells is increased along with an increase in carbohydrate metabolism. The efficiency of the glyoxalase system, consisting of glyoxalase 1 (GlxI) and glyoxalase 2 (GlxII), is cruci...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Lee, Der-Yen, Lin, Yu-Chin, Chang, Geen-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7926409/
https://ncbi.nlm.nih.gov/pubmed/33671767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10020326
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