EDEM3 Domains Cooperate to Perform Its Overall Cell Functioning

EDEM3 recognizes and directs misfolded proteins to the ER-associated protein degradation (ERAD) process. EDEM3 was predicted to act as lectin or as a mannosidase because of its homology with the GH47 catalytic domain of the Man1B1, but the contribution of the other regions remained unresolved. Here,...

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Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Manica, Georgiana, Ghenea, Simona, Munteanu, Cristian V. A., Martin, Eliza C., Butnaru, Cristian, Surleac, Marius, Chiritoiu, Gabriela N., Alexandru, Petruta R., Petrescu, Andrei-Jose, Petrescu, Stefana M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7926307/
https://ncbi.nlm.nih.gov/pubmed/33671632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22042172
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